Vacterl Association with Hydrocephaly, X-Linked, also known as vacterl association with hydrocephalus, is related to vacterl association, x-linked, with or without hydrocephalus and vater/vacterl association. An important gene associated with Vacterl Association with Hydrocephaly, X-Linked is ZIC3 (Zic Family Member 3). Related phenotype is Synthetic lethal with MLN4924 (a NAE inhibitor).