Uveitis

Uveitis is related to intermediate uveitis and blau syndrome. An important gene associated with Uveitis is NOD2 (Nucleotide Binding Oligomerization Domain Containing 2), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Lidocaine and Infliximab have been mentioned in the context of this disorder. Affiliated tissues include eye and retina, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Synthetic lethal with MLN4924 (a NAE inhibitor)