Uremia, also known as uremia of renal origin, is related to hyperparathyroidism and glomerulonephritis. An important gene associated with Uremia is EPO (Erythropoietin), and among its related pathways/superpathways are PI3K-Akt signaling pathway and Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs). The drugs Gabapentin and Histamine have been mentioned in the context of this disorder. Affiliated tissues include kidney and pancreas, and related phenotypes are homeostasis/metabolism and growth/size/body region