Unilateral Retinoblastoma

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Basic Information

Medical Symptom

Gene & Mutation

Related Drugs

Disease Model

References Literature

Unilateral Retinoblastoma is related to retinoblastoma and pineoblastoma. An important gene associated with Unilateral Retinoblastoma is MYCN (MYCN Proto-Oncogene, BHLH Transcription Factor), and among its related pathways/superpathways are Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) and Cell cycle. The drugs Carboplatin and Topotecan have been mentioned in the context of this disorder. Affiliated tissues include eye and pineal, and related phenotypes are nervous system and renal/urinary system

Related ID：

MALACARDS：UNL002