Type 2 Diabetes Mellitus, also known as insulin resistance, is related to diabetes mellitus and maturity-onset diabetes of the young, type 8, with exocrine dysfunction, and has symptoms including angina pectoris, tremor and equilibration disorder. An important gene associated with Type 2 Diabetes Mellitus is IRS1 (Insulin Receptor Substrate 1), and among its related pathways/superpathways are ERK Signaling and Nervous system development. The drugs Thrombin and Alprostadil have been mentioned in the context of this disorder. Affiliated tissues include Pancreas, Adipose and bone marrow, and related phenotypes are type ii diabetes mellitus and insulin resistance