Tatton-Brown-Rahman Syndrome (TBRS)

Tatton-Brown-Rahman Syndrome, also known as tatton-brown-rahman overgrowth syndrome, is related to overgrowth syndrome and adult syndrome. An important gene associated with Tatton-Brown-Rahman Syndrome is DNMT3A (DNA Methyltransferase 3 Alpha), and among its related pathways/superpathways are Chromatin Regulation / Acetylation and One-carbon metabolism and related pathways. The drugs Sotalol and Cocaine have been mentioned in the context of this disorder. Affiliated tissues include myeloid and bone marrow, and related phenotypes are macrocephaly and proportionate tall stature