Tetralogy of Fallot, also known as ventricular septal defect with pulmonary stenosis or atresia, dextraposition of aorta, and hypertrophy of right ventricle, is related to congenital heart defects, multiple types, 4 and ventricular septal defect. An important gene associated with Tetralogy of Fallot is JAG1 (Jagged Canonical Notch Ligand 1), and among its related pathways/superpathways are Nervous system development and Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers. The drugs Eplerenone and Antihypertensive Agents have been mentioned in the context of this disorder. Affiliated tissues include heart and trachea, and related phenotypes are abnormal nasal morphology and intrauterine growth retardation