Trypanosomiasis is related to sleeping sickness and chagas disease. An important gene associated with Trypanosomiasis is APOL1 (Apolipoprotein L1), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Nifurtimox and Eflornithine have been mentioned in the context of this disorder. Affiliated tissues include heart and bone marrow, and related phenotypes are homeostasis/metabolism and neoplasm