Tropical Sprue, also known as tropical steatorrhea, is related to celiac disease 1 and diarrhea. An important gene associated with Tropical Sprue is TOR1A (Torsin Family 1 Member A), and among its related pathways/superpathways are Transport of inorganic cations/anions and amino acids/oligopeptides and Metabolism of water-soluble vitamins and cofactors. The drugs Vaccines and Rifaximin have been mentioned in the context of this disorder. Affiliated tissues include small intestine and adrenal gland.