Transposition of the Great Arteries (TGA)

Alias:
Transposition of the Great Vessels
Great Vessels Transposition
Complete Transposition
Tga
Tgv
Transposition of the Great Arteries, Dextro-Looped 1
Complete Tga - [transposition of the Great Arteries]
Discordant Ventriculoarterial Connection
Complete Transposition of Great Vessels
Tga - [transposition of Great Arteries]
Tgv - [transposition of Great Vessels]
Great Vessels Complete Transposition
Transposition of Great Vessels Nos
Total Great Vessel Transposition
Transposition of Great Arteries
Transposition of Great Vessels
Transposed Vessels Nos
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Transposition of the Great Arteries, also known as transposition of the great vessels, is related to transposition of the great arteries, dextro-looped and double outlet right ventricle. An important gene associated with Transposition of the Great Arteries is GATA4 (GATA Binding Protein 4), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers and Endoderm differentiation. The drugs Mechlorethamine and Eplerenone have been mentioned in the context of this disorder. Affiliated tissues include heart and skin.
Related ID:
ICD11:429190257

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
--
Unknown
1-9/100000
2
49
--

Medical Symptom

#
Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Gene
Function
Score
Mutations
No data available

Related Drugs

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CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

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PMID
Journal
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IF
No Data Found!
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