Trench Fever, also known as his-werner disease, is related to pediculus humanus corporis infestation and bartonellosis. An important gene associated with Trench Fever is MT-CYB (Mitochondrially Encoded Cytochrome B), and among its related pathways/superpathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and Cytoprotection by HMOX1. Affiliated tissues include bone and endothelial.