Trigeminal Nerve Disease, also known as disorders of the fifth cranial nerve, is related to sensory peripheral neuropathy and trigeminal neuralgia, and has symptoms including atypical facial pain and neurologic symptoms. An important gene associated with Trigeminal Nerve Disease is SCN9A (Sodium Voltage-Gated Channel Alpha Subunit 9), and among its related pathways/superpathways are Nervous system development and Activation of cAMP-Dependent PKA. The drugs Acetylcholine and Cholinergic Agents have been mentioned in the context of this disorder. Affiliated tissues include brain and cortex, and related phenotypes are nervous system and growth/size/body region