Tenosynovial Giant Cell Tumor (TGCT)

Tenosynovial Giant Cell Tumor, also known as fibrous histiocytoma of tendon sheath, is related to malignant giant cell tumor of the tendon sheath and pigmented villonodular synovitis. An important gene associated with Tenosynovial Giant Cell Tumor is CSF1R (Colony Stimulating Factor 1 Receptor), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Antibodies and Immunoglobulins have been mentioned in the context of this disorder. Affiliated tissues include bone and testis, and related phenotypes are arthralgia and joint stiffness