Talipes Equinovarus

Talipes Equinovarus, also known as congenital talipes equinovarus, is related to kabuki syndrome 1 and scoliosis. An important gene associated with Talipes Equinovarus is PITX1 (Paired Like Homeodomain 1), and among its related pathways/superpathways is Syndecan-1-mediated signaling events. The drugs Clonidine and Acetylcholine have been mentioned in the context of this disorder. Affiliated tissues include brain and bone, and related phenotypes are growth/size/body region and embryo