Thyroid Carcinoma, Familial Medullary (MTC)

Alias:
Familial Medullary Thyroid Carcinoma
Medullary Thyroid Carcinoma
Mtc
Medullary Carcinoma with Amyloid Stroma, Unspecified Site
Medullary Carcinoma with Amyloid Stroma of Thyroid
Carcinoma, Thyroid, Medullary, Familial
Medullary Carcinoma of Thyroid
Thyroid Carcinoma Medullary
Familial Mtc
Fmtc
Mtc1
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
Thyroid Carcinoma, Familial Medullary, also known as familial medullary thyroid carcinoma, is related to multiple endocrine neoplasia, type iia and multiple endocrine neoplasia, type iib. An important gene associated with Thyroid Carcinoma, Familial Medullary is RET (Ret Proto-Oncogene), and among its related pathways/superpathways are RAF/MAP kinase cascade and Signal Transduction. The drugs D-Tyrosine and 3-Iodobenzylguanidine have been mentioned in the context of this disorder. Affiliated tissues include thyroid and lymph node, and related phenotypes are medullary thyroid carcinoma and nodular goiter
Related ID:
MESH:C536911
ICD11:578519098

Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
AD
Adult
1-9/100000
32
403
70

Medical Symptom

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Categorization
Description
HPO Frequency
Orphanet Frequency
HPO Source Accession
No data available

Gene & Mutation

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Gene
Function
Score
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
No data available

Disease Model

Category
Name
MGI
Related Gene
Strain of Origin
Publications
No data available

References Literature

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PMID
Journal
Year
IF
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