Thyroid Hormone Resistance, Selective Pituitary (PRTH)

Thyroid Hormone Resistance, Selective Pituitary, also known as selective pituitary resistance to thyroid hormone, is related to thyroid hormone resistance, generalized, autosomal recessive and pituitary adenoma. An important gene associated with Thyroid Hormone Resistance, Selective Pituitary is THRB (Thyroid Hormone Receptor Beta), and among its related pathways/superpathways are Transcription_Role of VDR in regulation of genes involved in osteoporosis and Thyroid hormones production and peripheral downstream signaling effects. The drugs Pembrolizumab and Immune Checkpoint Inhibitors have been mentioned in the context of this disorder. Affiliated tissues include thyroid and pituitary, and related phenotypes are hyperthyroidism and elevated circulating thyroid-stimulating hormone concentration