Thyroid Crisis, also known as thyrotoxic crisis, is related to hypothyroidism, congenital, nongoitrous, 1 and graves' disease. An important gene associated with Thyroid Crisis is TG (Thyroglobulin), and among its related pathways/superpathways are Thyroid hormones production and peripheral downstream signaling effects and Thyroxine (thyroid hormone) production. Affiliated tissues include thyroid and heart.