Thrombophilia Due to Activated Protein C Resistance (THPH2)

Alias:

Activated Protein C Resistance

Apc Resistance

Thrombophilia Due to Deficiency of Activated Protein C Cofactor

Thrombophilia Due to Factor V Leiden

Proc Cofactor Deficiency

Pccf Deficiency

Thrombophilia V

Thph2

Thrombophilia, Susceptibility to, Due to Factor V Leiden

Thrombophilia, Susceptibility to, Due to Activated Protein C Resistance

Thrombophilia 2 Due to Activated Protein C Resistance

Thrombophilia, Due to Activated Protein C Resistance

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Basic Information

Medical Symptom

Gene & Mutation

Related Drugs

Disease Model

References Literature

Thrombophilia Due to Activated Protein C Resistance, also known as activated protein c resistance, is related to pregnancy loss, recurrent 1 and polycythemia. An important gene associated with Thrombophilia Due to Activated Protein C Resistance is F5 (Coagulation Factor V), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. The drugs Atezolizumab and Bevacizumab have been mentioned in the context of this disorder. Affiliated tissues include lung and bone marrow, and related phenotypes are hypercoagulability and deep venous thrombosis

Related ID：

MALACARDS：THR082

OMIM：188055

MESH：C566056