Thrombasthenia

Thrombasthenia is related to bleeding disorder, platelet-type, 24 and bleeding disorder, platelet-type, 16. An important gene associated with Thrombasthenia is ITGA2B (Integrin Subunit Alpha 2b), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and PI3K-Akt signaling pathway. The drugs Fludarabine and Cyclophosphamide have been mentioned in the context of this disorder. Affiliated tissues include whole blood and bone marrow.