Thrombosis, also known as thrombosis of blood vessel, is related to thrombophilia due to thrombin defect and portal vein thrombosis. An important gene associated with Thrombosis is F2 (Coagulation Factor II, Thrombin), and among its related pathways/superpathways are Metabolism of proteins and Signal Transduction. The drugs Abciximab and Alprostadil have been mentioned in the context of this disorder. Affiliated tissues include liver and endothelial, and related phenotypes are homeostasis/metabolism and nervous system