Thoracic Outlet Syndrome, also known as thoracic outlet compression syndrome, is related to plexopathy and thrombophilia due to thrombin defect, and has symptoms including back pain, headache and pain. An important gene associated with Thoracic Outlet Syndrome is PLAT (Plasminogen Activator, Tissue Type). The drugs Ropivacaine and Acetylcholine have been mentioned in the context of this disorder. Affiliated tissues include spinal cord and bone, and related phenotypes are paresthesia and muscle weakness