Thiopurines, Poor Metabolism of, 1 (THPM1)

Thiopurines, Poor Metabolism of, 1, also known as thiopurine s-methyltransferase deficiency, is related to leukemia, acute lymphoblastic and thiopurine s methyltranferase deficiency. An important gene associated with Thiopurines, Poor Metabolism of, 1 is TPMT (Thiopurine S-Methyltransferase), and among its related pathways/superpathways are Metabolism and Nuclear receptors meta-pathway. Affiliated tissues include bone marrow and bone, and related phenotypes are abnormality of metabolism/homeostasis and abnormality of blood and blood-forming tissues