T-Cell Prolymphocytic Leukemia, also known as t-cell chronic lymphocytic leukemia, is related to prolymphocytic leukemia and ataxia-telangiectasia. An important gene associated with T-Cell Prolymphocytic Leukemia is ATM (ATM Serine/Threonine Kinase), and among its related pathways/superpathways are Akt Signaling and TCR Signaling (Qiagen). The drugs Temsirolimus and Mycophenolic acid have been mentioned in the context of this disorder. Affiliated tissues include bone marrow and spleen.