T-Cell Large Granular Lymphocyte Leukemia (T-LGL)

Alias:
Proliferation of Large Granular Lymphocytes
Large Granular Lymphocytic Leukemia
T-Cell Lgl Leukemia
T-Lgl
T-Cell Large Granular Lymphocyte Leukaemia
Large Granular Lymphocytic Leukaemia
Leukemia, Large Granular Lymphocytic
Leukemia Lymphocytic Large Granular
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Basic Information
Medical Symptom
Gene & Mutation
Related Drugs
Disease Model
References Literature
T-Cell Large Granular Lymphocyte Leukemia, also known as proliferation of large granular lymphocytes, is related to pure red-cell aplasia and lymphoproliferative syndrome. An important gene associated with T-Cell Large Granular Lymphocyte Leukemia is STAT3 (Signal Transducer And Activator Of Transcription 3), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Prednisone and Thalidomide have been mentioned in the context of this disorder. Affiliated tissues include bone marrow and t cells, and related phenotypes are cellular and immune system
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Basic Information

Inheritance
Age of Onset
Prevalence
Related Gene
Related Mouse Models
Reference
MALACARDS
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Adult
1-9/1000000
19
204
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Medical Symptom

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Description
HPO Frequency
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HPO Source Accession
No data available

Gene & Mutation

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Related Drugs

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No data available

Disease Model

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Name
MGI
Related Gene
Strain of Origin
Publications
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References Literature

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