T-Cell Large Granular Lymphocyte Leukemia, also known as proliferation of large granular lymphocytes, is related to pure red-cell aplasia and lymphoproliferative syndrome. An important gene associated with T-Cell Large Granular Lymphocyte Leukemia is STAT3 (Signal Transducer And Activator Of Transcription 3), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Prednisone and Thalidomide have been mentioned in the context of this disorder. Affiliated tissues include bone marrow and t cells, and related phenotypes are cellular and immune system