Tubulointerstitial Kidney Disease, Autosomal Dominant, 1 (ADTKD1)

Tubulointerstitial Kidney Disease, Autosomal Dominant, 1, also known as familial juvenile hyperuricemic nephropathy, is related to nephronophthisis and hyperuricemic nephropathy, familial juvenile, 3. An important gene associated with Tubulointerstitial Kidney Disease, Autosomal Dominant, 1 is UMOD (Uromodulin), and among its related pathways/superpathways are NPHP1 deletion syndrome and Uricosurics Pathway, Pharmacodynamics. The drugs Temsirolimus and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include kidney and liver, and related phenotypes are renal insufficiency and hyperuricemia