Tubulinopathy-Associated Dysgyria

Tubulinopathy-Associated Dysgyria, also known as brain stem asymmetry-superior cerebellar and basal ganglia dysplasia syndrome, is related to fourth cranial nerve palsy and tukel syndrome. An important gene associated with Tubulinopathy-Associated Dysgyria is TUBA1A (Tubulin Alpha 1a), and among its related pathways/superpathways are Signaling by Rho GTPases and Class I MHC mediated antigen processing and presentation. Affiliated tissues include brain and cerebellum, and related phenotypes are global developmental delay and microcephaly