Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus, also known as lupus nephritis, is related to lupus erythematosus and autoimmune disease, and has symptoms including exanthema, pruritus and lupus-like rash. An important gene associated with Systemic Lupus Erythematosus is TREX1 (Three Prime Repair Exonuclease 1), and among its related pathways/superpathways are Innate Immune System and NF-kappaB Signaling. The drugs Artesunate and Sulfamethoxazole have been mentioned in the context of this disorder. Affiliated tissues include Umbilical Cord, bone marrow and skin, and related phenotypes are proteinuria and antinuclear antibody positivity