Syndromic X-Linked Intellectual Disability Cabezas Type (MRSS)

Syndromic X-Linked Intellectual Disability Cabezas Type, also known as mental retardation, x-linked, with short stature, hypogonadism, and abnormal gait, is related to scleroderma, familial progressive and intellectual developmental disorder, x-linked, syndromic, cabezas type, and has symptoms including tremor and gait ataxia. An important gene associated with Syndromic X-Linked Intellectual Disability Cabezas Type is CUL4B (Cullin 4B), and among its related pathways/superpathways are Class I MHC mediated antigen processing and presentation and Development_Hedgehog and PTH signaling pathways in bone and cartilage development. Affiliated tissues include skin and lung, and related phenotype is Increased cell death in HCT116 cells.