Syndactyly, Type Iv, also known as syndactyly type 4, is related to triphalangeal thumb with polysyndactyly and polydactyly, preaxial ii. An important gene associated with Syndactyly, Type Iv is LMBR1 (Limb Development Membrane Protein 1), and among its related pathways/superpathways are Hedgehog signaling pathway and Hedgehog signaling events mediated by Gli proteins. Affiliated tissues include bone, and related phenotypes are hand polydactyly and camptodactyly of finger