Severe Cutaneous Adverse Reaction (SJS)

Alias:

Stevens-Johnson Syndrome

Toxic Epidermal Necrolysis

Susceptibility to Severe Cutaneous Adverse Reaction

Dermatostomatitis, Stevens Johnson Type

Lyell Syndrome

Hypersensitivity Syndrome, Carbamazepine-Induced, Susceptibility to

Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum

Severe Cutaneous Adverse Reaction, Susceptibility to

Hypersensitivity Syndrome, Carbamazepine-Induced

Toxic Epidermal Necrolysis, Susceptibility to

Stevens-Johnson Syndrome, Susceptibility to

Dermatostomatitis Stevens Johnson Type

Drug-Induced Stevens Johnson Syndrome

Ten - [toxic Epidermal Necrolysis]

Sjs

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Basic Information

Medical Symptom

Gene & Mutation

Related Drugs

Disease Model

References Literature

Severe Cutaneous Adverse Reaction, also known as stevens-johnson syndrome, is related to sjogren syndrome and dry eye syndrome. An important gene associated with Severe Cutaneous Adverse Reaction is HLA-B (Major Histocompatibility Complex, Class I, B), and among its related pathways/superpathways are NF-kappaB Signaling and Apoptosis and Autophagy. The drugs Lenograstim and Pharmaceutical Solutions have been mentioned in the context of this disorder. Affiliated tissues include skin and eye, and related phenotypes are nausea and vomiting and dysphagia

Related ID：

MALACARDS：SVR097

OMIM：608579

MESH：D013262

ICD11：1575072695