Stuttering, also known as stammering, is related to speech and communication disorders and speech disorder, and has symptoms including stuttering, acquired, abdominal pain and back pain. An important gene associated with Stuttering is AP4E1 (Adaptor Related Protein Complex 4 Subunit Epsilon 1), and among its related pathways/superpathways are Primary ovarian insufficiency and Methylphenidate Pathway, Pharmacodynamics. The drugs Central Nervous System Stimulants and Ramipril have been mentioned in the context of this disorder. Affiliated tissues include brain and thalamus, and related phenotypes are nervous system and homeostasis/metabolism