Striatal Degeneration, Autosomal Dominant 1, also known as striatal degeneration, autosomal dominant, is related to striatal degeneration, autosomal dominant 2 and spasmodic dysphonia. An important gene associated with Striatal Degeneration, Autosomal Dominant 1 is PDE8B (Phosphodiesterase 8B). Affiliated tissues include caudate nucleus and brain, and related phenotypes are dysarthria and abnormality of movement