Surfactant Dysfunction

Surfactant Dysfunction, also known as pulmonary surfactant metabolism dysfunction, is related to meconium aspiration syndrome and lung disease. An important gene associated with Surfactant Dysfunction is ABCA3 (ATP Binding Cassette Subfamily A Member 3), and among its related pathways/superpathways are Infectious disease and Metabolism of proteins. The drugs Nitric Oxide and Calfactant have been mentioned in the context of this disorder. Affiliated tissues include lung and brain, and related phenotypes are Increased shRNA abundance (Z-score > 2) and respiratory system