Spitzoid Melanoma

Spitzoid Melanoma, also known as atypical spitz nevus, is related to spitz nevus and melanocytic nevus syndrome, congenital. An important gene associated with Spitzoid Melanoma is ROS1 (ROS Proto-Oncogene 1, Receptor Tyrosine Kinase), and among its related pathways/superpathways are Apoptotic Pathways in Synovial Fibroblasts and ERK Signaling. Affiliated tissues include skin and lymph node, and related phenotypes are Decreased viability and Increased shRNA abundance (Z-score > 2)