Spastic Ataxia 3

Spastic Ataxia 3 is related to spastic ataxia 3, autosomal recessive and cortical dysplasia, complex, with other brain malformations 2, and has symptoms including cerebellar ataxia, muscle spasticity and gait ataxia. An important gene associated with Spastic Ataxia 3 is MARS2 (Methionyl-TRNA Synthetase 2, Mitochondrial). Related phenotype is Decreased viability after Maraba virus infection.