Spastic Paraplegia 53, Autosomal Recessive (SPG53)

Spastic Paraplegia 53, Autosomal Recessive, also known as hereditary spastic paraplegia 53, is related to spastic paraplegia 52, autosomal recessive and low compliance bladder, and has symptoms including clonus An important gene associated with Spastic Paraplegia 53, Autosomal Recessive is VPS37A (VPS37A Subunit Of ESCRT-I), and among its related pathways/superpathways are Vesicle-mediated transport and trans-Golgi Network Vesicle Budding. Affiliated tissues include brain, and related phenotypes are clonus and hyperreflexia in upper limbs