Spastic Paraplegia 13, Autosomal Dominant (SPG13)

Spastic Paraplegia 13, Autosomal Dominant, also known as spg13, is related to hypomyelinating leukodystrophy and spastic paraplegia 20, autosomal recessive, and has symptoms including urgency of micturition and abnormal pyramidal signs. An important gene associated with Spastic Paraplegia 13, Autosomal Dominant is HSPD1 (Heat Shock Protein Family D (Hsp60) Member 1). Affiliated tissues include brain, and related phenotypes are spastic paraplegia and urinary bladder sphincter dysfunction