Spastic Paraplegia 44, Autosomal Recessive (SPG44)

Spastic Paraplegia 44, Autosomal Recessive, also known as hereditary spastic paraplegia 44, is related to pelizaeus-merzbacher-like disease and hypomyelinating leukoencephalopathy, and has symptoms including cerebellar ataxia and action tremor. An important gene associated with Spastic Paraplegia 44, Autosomal Recessive is GJC2 (Gap Junction Protein Gamma 2), and among its related pathways/superpathways is Gap junction trafficking. Affiliated tissues include eye and brain, and related phenotypes are ataxia and dysarthria