Spastic Paraparesis

Spastic Paraparesis is related to spastic paraplegia 20, autosomal recessive and spastic paraplegia 9a, autosomal dominant. An important gene associated with Spastic Paraparesis is SPAST (Spastin), and among its related pathways/superpathways are Metabolism and Ether lipid biosynthesis. The drugs Pentoxifylline and Vasodilator Agents have been mentioned in the context of this disorder. Affiliated tissues include spinal cord and t cells, and related phenotypes are growth/size/body region and nervous system