Spinocerebellar Ataxia 8 (SCA8)

Spinocerebellar Ataxia 8, also known as spinocerebellar ataxia type 8, is related to spinocerebellar ataxia, autosomal recessive 8 and mitochondrial dna depletion syndrome 7, and has symptoms including muscle spasticity, tremor and abnormal pyramidal signs. An important gene associated with Spinocerebellar Ataxia 8 is ATXN8OS (ATXN8 Opposite Strand LncRNA). Affiliated tissues include spinal cord and eye, and related phenotypes are spasticity and hyperreflexia