Spinocerebellar Ataxia 1 (SCA1)

Spinocerebellar Ataxia 1, also known as spinocerebellar ataxia type 1, is related to spinocerebellar ataxia 10 and spinocerebellar ataxia 7, and has symptoms including muscle spasticity, abnormal pyramidal signs and abnormality of extrapyramidal motor function. An important gene associated with Spinocerebellar Ataxia 1 is ATXN1 (Ataxin 1), and among its related pathways/superpathways is Maturation of protein E. The drugs Glutamic acid and Lithium carbonate have been mentioned in the context of this disorder. Affiliated tissues include spinal cord and eye, and related phenotypes are peripheral neuropathy and progressive cerebellar ataxia