Spinocerebellar Ataxia 21 (SCA21)

Spinocerebellar Ataxia 21, also known as spinocerebellar ataxia type 21, is related to spinocerebellar ataxia, autosomal recessive 21 and autosomal dominant cerebellar ataxia, and has symptoms including cerebellar ataxia, tremor and cogwheel rigidity. An important gene associated with Spinocerebellar Ataxia 21 is TMEM240 (Transmembrane Protein 240), and among its related pathways/superpathways is Ciliopathies. Affiliated tissues include spinal cord and cerebellum, and related phenotypes are abnormality of extrapyramidal motor function and gait ataxia