Spondylolysis, also known as acquired spondylolysis, is related to spondylolisthesis and spondylosis, and has symptoms including back pain An important gene associated with Spondylolysis is SLC26A2 (Solute Carrier Family 26 Member 2), and among its related pathways/superpathways are Extracellular matrix organization and Elastic fibre formation. The drugs Bupivacaine and Anesthetics have been mentioned in the context of this disorder. Affiliated tissues include bone and bone marrow, and related phenotypes are limbs/digits/tail and craniofacial