Split-Hand/foot Malformation 2, also known as split hand/foot malformation 2, is related to split hand-foot malformation and chromosome 2q35 duplication syndrome. An important gene associated with Split-Hand/foot Malformation 2 is SHFM2 (Split Hand/Foot Malformation (Ectrodactyly) Type 2). Affiliated tissues include bone and prostate, and related phenotypes are split hand and finger syndactyly