Split-Foot Malformation with Mesoaxial Polydactyly, also known as split-foot malformation-mesoaxial polydactyly syndrome, is related to split-hand/foot malformation 1. An important gene associated with Split-Foot Malformation with Mesoaxial Polydactyly is MAP3K20 (Mitogen-Activated Protein Kinase Kinase Kinase 20). Affiliated tissues include skin and bone, and related phenotypes are split foot and bilateral sensorineural hearing impairment