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ENSplenomegaly
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Splenomegaly is related to myeloid and lymphoid neoplasms associated with pdgfra rearrangement and leukemia, chronic myeloid. An important gene associated with Splenomegaly is SBDS (SBDS Ribosome Maturation Factor), and among its related pathways/superpathways are NF-kappaB Signaling and Hematopoietic Stem Cells and Lineage-specific Markers. The drugs Obinutuzumab and Lenalidomide have been mentioned in the context of this disorder. Affiliated tissues include spleen and bone marrow, and related phenotypes are Increased shRNA abundance (Z-score > 2) and homeostasis/metabolism
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MALACARDS
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