Sphingolipidosis

Sphingolipidosis, also known as sphingolipidoses, is related to combined saposin deficiency and metachromatic leukodystrophy. An important gene associated with Sphingolipidosis is PSAP (Prosaposin), and among its related pathways/superpathways are Metabolism and Sphingolipid metabolism. The drugs Benzocaine and Mycophenolic acid have been mentioned in the context of this disorder. Affiliated tissues include bone marrow and skin, and related phenotypes are shRNA abundance <= 50% and homeostasis/metabolism