Somatoform Disorder, also known as physiological malfunction arising from mental factor, is related to alexithymia and personality disorder, and has symptoms including dyspnea, headache and meningism. An important gene associated with Somatoform Disorder is SCN9A (Sodium Voltage-Gated Channel Alpha Subunit 9), and among its related pathways/superpathways are Activation of cAMP-Dependent PKA and Cardiac conduction. The drugs Tibolone and Medroxyprogesterone acetate have been mentioned in the context of this disorder. Affiliated tissues include small intestine and heart, and related phenotypes are nervous system and homeostasis/metabolism