Smith-Lemli-Opitz Syndrome (SLOS)

Smith-Lemli-Opitz Syndrome, also known as slos, is related to greenberg dysplasia and hypercholesterolemia, familial, 1, and has symptoms including constipation, seizures and vomiting. An important gene associated with Smith-Lemli-Opitz Syndrome is DHCR7 (7-Dehydrocholesterol Reductase), and among its related pathways/superpathways are Metabolism and Glucose / Energy Metabolism. The drugs Simvastatin and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include lung and eye, and related phenotypes are intellectual disability and hypotonia