Smoking As a Quantitative Trait Locus 3 (SQTL3)

Smoking As a Quantitative Trait Locus 3, also known as lung cancer susceptibility 2, is related to tobacco addiction and alcohol dependence. An important gene associated with Smoking As a Quantitative Trait Locus 3 is CHRNA3 (Cholinergic Receptor Nicotinic Alpha 3 Subunit), and among its related pathways/superpathways are Transmission across Chemical Synapses and Acetylcholine binding and downstream events. The drugs Oxytocin and Varenicline have been mentioned in the context of this disorder. Affiliated tissues include lung and brain, and related phenotype is Increased shRNA abundance (Z-score > 2).